Neuroinflammatory Responses After Experimental Diffuse Traumatic Brain Injury
نویسندگان
چکیده
منابع مشابه
Neuroinflammatory responses after experimental diffuse traumatic brain injury.
Little is known about microglial activation and macrophage localization after diffuse brain injury (DBI). DBI-mediated perisomatic traumatic axonal injury (TAI) was recently identified within the neocortex, hippocampus, and thalamus, providing an opportunity to characterize immune cell responses within diffusely injured brain loci uncomplicated by contusion. By using moderate midline/central fl...
متن کاملNeuroinflammatory responses to traumatic brain injury
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Despite increasing appreciation of the critical role that neuroinflammatory pathways play in brain injury and neurodegeneration, little is known about acute microglial reactivity following diffuse traumatic brain injury (TBI) - the most common clinical presentation that includes all concussions. Therefore, we investigated acute microglial reactivity using a porcine model of closed-head rotation...
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متن کاملNeuroinflammatory responses to traumatic brain injury: etiology, clinical consequences, and therapeutic opportunities
Traumatic brain injury (TBI) is a serious public health problem accounting for 1.4 million emergency room visits by US citizens each year. Although TBI has been traditionally considered an acute injury, chronic symptoms reminiscent of neurodegenerative disorders have now been recognized. These progressive neurodegenerative-like symptoms manifest as impaired motor and cognitive skills, as well a...
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ژورنال
عنوان ژورنال: Journal of Neuropathology & Experimental Neurology
سال: 2007
ISSN: 0022-3069,1554-6578
DOI: 10.1097/nen.0b013e3181588245